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Friday, October 16

Serotonergic psychedelics delay resting state neurovascular coupling dynamics

A bioRxiv preprint investigated how the psychedelics LSD and DMT alter resting state neurovascular coupling. Using a blind deconvolution algorithm on BOLD signals, the authors found that both drugs increased estimated hemodynamic delays in regions overlapping with serotonin receptor distributions. The findings suggest that vascular effects should be accounted for in future psychedelic neuroimaging studies.